Encephalopathy refers to any disease or disorder of the brain.
EX: Neonatal encephalopathy
Neonatal encephalopathy is “a clinically defined syndrome of disturbed neurological function in the earliest days of life in the term infant, manifested by difficulty with initiating and maintaining respiration, depression of tone and reflexes, sub normal level of consciousness and often seizures”.
Nelson KB, Leviton A. How much of neonatal encephalopathy is due to birth asphyxia? Am J Dis Child 1991;145(11):1325-31.